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Given these distinct pathophysiological dynamics and therapeutic priorities, stroke will not be discussed further in this review, which focuses instead on chronic neurological diseases characterized by progressive neuronal loss, complex molecular interactions, and the need for sustained neuroprotective strategies

This is mainly due to the fact that research has traditionally focused on well-known stress molecules like SA or JA, or simply measured the activity of selected redox enzymes

Junctions between intimately apposed cell membranes in the vertebrate brain

Inhibition of PDE4 phosphodiesterase activity induces growth suppression, apoptosis, glucocorticoid sensitivity, p53, and p21WAF1/CIP1 proteins in human acute lymphoblastic leukemia cells

Faghfouri, A